核纤层蛋白相关蛋白1B抗体
规格:1mg/1ml
英文名: LAP1B
别名: Lamin-associated protein 1B; Lamina associated polypeptide 1B; Lamina associated polypeptide 1C; LAP1; LAP1B; TOIP1_HUMAN; TOR1AIP1; Torsin A interacting protein 1; Torsin-1A-interacting protein 1.
分子量: 66kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human LAP1B
交叉反应:Human, Rat,
细胞定位:细胞核
核纤层蛋白相关蛋白1B抗体产品介绍:background: This gene encodes a type 2 integral membrane protein that binds A- and B-type laminins. The encoded protein localizes to the inner nuclear membrane and may be involved in maintaining the attachment of the nuclear membrane to the nuclear lamina during cell division. Alternate splicing results in multiple transcript variants. [provided by RefSeq,核纤层蛋白相关蛋白1B抗体 Jun 2012] Function: Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina. Subcellular Location: Nucleus inner membrane. Post-translational modifications: Phosphorylated upon DNA damage, probably by 核纤层蛋白相关蛋白1B抗体ATM or ATR. Similarity: Belongs to the TOR1AIP family. Gene ID: 26092 Database links: Entrez Gene: 26092 Human SwissProt: Q5JTV8 Human Unigene: 496459 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
核纤层蛋白相关蛋白1B抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 染色质和核信号 信号转导 细胞类型标志物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid