SGF29蛋白抗体
规格：1mg/1ml
英文名： SGF29
别名： CCDC101; Coiled coil domain containing 101; Coiled coil domain containing protein 101; Coiled-coil domain-containing protein 101; FLJ32446; OTTMUSP00000030606; SAGA associated factor 29 homolog; SAGA-
分子量： 33kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SGF29
交叉反应：Human, Mouse, Rat,
细胞定位：细胞核
SGF29蛋白抗体产品介绍：background: CCDC101 is a subunit of 2 histone acetyltransferase complexes: the ADA2A (TADA2A; MIM 602276)-containing (ATAC) complex and the SPT3 (SUPT3H; MIM 602947)-TAF9 (MIM 600822)-GCN5 (KAT2A; MIM 602301)/PCAF (KAT2B; MIM 602303) acetylase (STAGA) complex. Both of these complexes contain either GCN5 or PCAF, which are paralogous acetyltransferases (Wang et al., 2008 [PubMed 18838386]).[supplied by OMIM, Apr 2010] Function: Involved in transcriptional regulation, through association with histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. Specifically recognizes and binds SGF29蛋白抗体methylated 'Lys-4' of histone H3 (H3K4me), with a preferrence for trimethylated form (H3K4me3). In the SAGA-type complexes, required to recruit complexes to H3K4me. May be involved in MYC-mediated oncogenic transformation. Subcellular Location: Nucleus. Similarity: Belongs to the SGF29 family. Contains 1 SGF29 C-terminal domain. Database links: Entrez Gene: 112869 Human Entrez Gene: 75565 MouseSGF29蛋白抗体 Entrez Gene: 293488 Rat Omim: 613374 Human SwissProt: Q96ES7 Human SwissProt: Q9DA08 Mouse SwissProt: P0C606 Rat Unigene: 655476 Human Unigene: 45686 Mouse Unigene: 34983 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
SGF29蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid