白细胞介素增强子结合因子1抗体
规格：1mg/1ml
英文名： ILF1
别名： Cellular transcription factor ILF 1; Cellular transcription factor ILF-1; Cellular transcription factor ILF1; Forkhead box K2; Forkhead box protein K2; FOX K1; FOX K2; FOXK 1; FOXK 2; FOXK1; FOXK2; FO
分子量： 69kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ILF1
交叉反应：Human, Mouse, Rat, Pig,
细胞定位：细胞核
白细胞介素增强子结合因子1抗体产品介绍：background: ILF1 is a 660 amino acid protein that localizes to the nucleus and contains one FHA domain and one forkhead DNA-binding domain. Expressed in lymphoid and non-lymphoid cells, FOXK2 uses magnesium as a cofactor and binds to purine-rich motifs in select promoters, possibly playing a role in the regulation of viral and cellular promoter elements. FOXK2 exists as multiple alternatively spliced isoforms and is subject to DNA damage-dependent phosphorylation, probably by ATM or ATR. Function: Recognizes the core sequence 5'-TAAACA-3'. Binds to NFAT-like motifs (purine-rich) in the IL2 promoter. Also binds to HIV-1 long terminal repeat. May be involved in both positive and negative regulation of important viral and cellular promoter elements. Subcellular Location: Nucleus. Tissue 白细胞介素增强子结合因子1抗体Specificity: Expressed in both lymphoid and non-lymphoid cells. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Contains 1 FHA domain. Contains 1 fork-head DNA-binding domain. Gene ID: 3607 白细胞介素增强子结合因子1抗体Database links: Entrez Gene: 3607 Human Entrez Gene: 68837 Mouse Entrez Gene: 303753 Rat Omim: 147685 Human SwissProt: Q01167 Human SwissProt: Q3UCQ1 Mouse Unigene: 591140 Human Unigene: 209750 Mouse Unigene: 44253 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
白细胞介素增强子结合因子1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid