FBN3蛋白抗体
规格：1mg/1ml
英文名： FBN3
别名： Fibrillin 3; FBN3_HUMAN; KIAA1776.
分子量： 297kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FBN3
交叉反应：Human,
细胞定位：细胞浆
FBN3蛋白抗体产品介绍：background: This gene encodes a protein that belongs to the fibrillin gene family. Fibrillins are extracellular matrix molecules that assemble into microfibrils in many connective tissues. This gene is most highly expressed in fetal tissues and its protein product is localized to extracellular microfibrils of developing skeletal elements, skin, lung, kidney, and skeletal muscle. This gene is potentially involved in Weill-Marchesani syndrome. While several transcript variants may exist for this gene, their full-length natures have not been described to date. [provided by RefSeq, Jul 2008] Function: Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-containing microfibrils provide long-term force bearing structural support. FBN3蛋白抗体Subcellular Location: Secreted; extracellular space; extracellular matrix. Tissue Specificity: Predominantly expressed in connective tissues such as skeletal muscle, tendon, skin, perichondrium and periosteum. Highly expressed in fetal lung, brain, kidney. Expressed at low level in prostate, testis, mammary gland, uterus, ovary, placenta, bladder, adrenal gland, thyroid, fetal thymus, fetal liver, liver, fetal heart FBN3蛋白抗体and heart. Post-translational modifications: Probably forms intermolecular disulfide bonds either with other FBN3 molecules or with other components of the microfibrils (By similarity). Similarity: Belongs to the fibrillin family. Contains 44 EGF-like domains. Contains 9 TB (TGF-beta binding) domains. Gene ID: 84467 Database links: Entrez Gene: 84467 Human Omim: 608529 Human SwissProt: Q75N90 Human Unigene: 370362 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FBN3蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 结合蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid