大脑边缘系统相关膜蛋白抗体
规格：1mg/1ml
英文名： LSAMP
别名： IgLON family member 3; IGLON3; Lam; LAMP; Limbic system associated membrane protein; Limbic system associated membrane protein precursor; Limbic system-associated membrane protein; LSAMP; LSAMP_HUMAN.
分子量： 32kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human LSAMP
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞膜
大脑边缘系统相关膜蛋白抗体产品介绍：background: LSAMP is a neuronal surface glycoprotein found in cortical and subcortical regions of the limbic system expressed on the surface of somata and proximal dendrites of neurons. It is a member of the immunoglobulin (Ig) superfamily and belongs to the IgLON subfamily of cell adhesion molecules. LSAMP contains three Ig domains and a glycosylphosphatidylinositol anchor. It is a highly conserved protein between rodents and humans (99% sequence identity) and it is involved in the regulation of neurite outgrowth大脑边缘系统相关膜蛋白抗体 and mediation of proper circuit formation of limbic pathways. This suggests that LSAMP plays an important role in the development and function of the limbic system. In addition, LSAMP may function as a tumor suppressor in renal carcinomas. Function: Mediates selective neuronal growth and axon targeting. Contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system. Essential for normal growth of the hyppocampal mossy fiber projection. Subcellular Location: Cell membrane. Tissue Specificity:大脑边缘系统相关膜蛋白抗体 Expressed on limbic neurons and fiber tracts as well as in single layers of the superior colliculus, spinal chord and cerebellum. Similarity: Belongs to the immunoglobulin superfamily. IgLON family. Contains 3 Ig-like C2-type (immunoglobulin-like) domains. Database links: UniProtKB/Swiss-Prot: Q13449.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
大脑边缘系统相关膜蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 细胞粘附分子 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid