GalNAc-T14抗体
规格：1mg/1ml
英文名： GALNT14
别名： GalNAc T14; GalNAc-T14; Galnt14; GALNT14; GalNac-T10; GALNT15; pp-GaNTase 14; GLT14_HUMAN; Polypeptide GalNAc transferase 14; Polypeptide N acetylgalactosaminyltransferase 14; Polypeptide N-acetylgala
分子量： 64kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GALNT14
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆
GalNAc-T14抗体产品介绍：background: This gene encodes a Golgi protein which is a member of the polypeptide N-acetylgalactosaminyltransferase (ppGalNAc-Ts) protein family. These enzymes catalyze the transfer of N-acetyl-D-galactosamine (GalNAc) to the hydroxyl groups on serines and threonines in target peptides. The encoded protein has been shown to transfer GalNAc to large proteins like mucins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]. Function: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on theGalNAc-T14抗体 protein receptor. Displays activity toward mucin-derived peptide substrates such as Muc2, Muc5AC, Muc7, and Muc13 (-58). May be involved in O-glycosylation in kidney. Subcellular Location: Golgi apparatus membrane; Single-pass type II membrane protein. Tissue Specificity: Highly expressed in fetal and ***** kidney. Widely expressed at low level. Weakly expressed in whole brain, cerebellum, thymus, lung, GalNAc-T14抗体mammary gland, liver, stomach, small intestine, colon, pancreas, spleen, bladder, uterus, placenta, testis, ovary, skeletal muscle, leukocyte, B-cell, bone marrow, fetal brain, fetal thymus, fetal lung, fetal liver, fetal small intestine, fetal spleen, fetal skeletal and fetus. Similarity: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. Contains 1 ricin B-type lectin domain. Database links: NCBI Reference Sequence: NP_078848 UniProtKB/Swiss-Prot: Q96FL9 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
GalNAc-T14抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 通道蛋白 细胞类型标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid