kappa型**受体抗体
规格：1mg/1ml
英文名： kappa Opioid receptor
别名： Kappa type opioid receptor; KOR 1; KOR; Opiate receptor kappa 1; OPRK 1; OPRK; OPRK1; Oprk2; R21; OPRK_HUMAN.
分子量： 43kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human kappa Op
交叉反应：Human, Mouse, Rat,
细胞定位：
kappa型**受体抗体产品介绍：background: Opioid is the term used to designate a group of compounds that are opium-like in their properties. These drugs have effects on perception of pain, consciousness, motor control, mood, and autonomic function, and can induce physical dependence. Pharmacological studies suggested that there are at least 3 major classes of opioid receptors, designated delta, kappa, and mu. They differ in their affinity for various opioid ligands and in their cellular distribution. Studies of the receptors in the mouse and rat show that they are structurally related and are members of the family of 7 transmembrane-spanning G protein-coupled receptors. The kappa kappa型**受体抗体opiod receptor inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. It is the receptor for beta-endorphin. Function: Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for dynorphins. May play a role in arousal and regulation of autonomic and neuroendocrine functions. Subunit: kappa型**受体抗体Interacts with SLC9A3R1. Interacts with GABARAPL1. Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 4986 Database links: Entrez Gene: 4986 Human Omim: 165196 Human SwissProt: P41145 Human Unigene: 106795 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. kappa型**受体在人脑和胎盘组织中有分布。κ- 受体参与镇痛 ，且与神经***及**调节有关。此外，κ受体也调控****样脊髓镇痛、**和瞳孔缩小。κ-**受体由380个氨基酸组成，同样属于G蛋白偶联受体家族。
kappa型**受体抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid