NDUFAF4抗体
规格：1mg/1ml
英文名： NDUFAF4
别名： NDUF4_HUMAN; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4; Hormone-regulated proliferation-associated protein of 20 kDa; bA22L21.1; C6orf66; HRPAP20; HSPC125; My013.
分子量： 19kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NDUFAF4
交叉反应：Human, Mouse, Rat,
细胞定位：
NDUFAF4抗体产品介绍：background: NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene are a cause of mitochondrial complex I deficiency. [provided by RefSeq, Oct 2009]. Function: Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). May be involved in cell proliferation and survival of hormone-dependent tumor cells. May be a regulator of breast tumor cell invasion. Subunit: Binds calmodulin. Interacts with NDUFAF3. Subcellular Location: Mitochondrion. Post-translational modifications: Phosphorylated on serine. Prolactin NDUFAF4抗体stimulate serine phosphorylation. DISEASE: Mitochondrial complex I deficiency (MT-C1D) [MIM:252010]: A disorder of the mitochondrial respiratory chain that causes a wide range of clinical manifestations from lethal neonatal disease to *****-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, NDUFAF4抗体Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the NDUFAF4 family. Database links: UniProtKB/Swiss-Prot: Q9P032.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
NDUFAF4抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：线粒体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid